[ crispr_screen ]

Introduction

crispr_screen is a free, open-source command-line tool that enables easy and efficient differential expression analysis for CRISPR screens.

It is a recreation of the MAGeCK algorithm, which is a form of the DESeq method specifically applied for CRISPR screens. This tool extends the MAGeCK algorithm with the MAGeCK-INC method, but also implements the αRRA algorithm described in the original MAGeCK paper.

It is a drop-in replacement of current differential expression analyses that is faster, more stable, and easier to use.