[ crispr_screen
]
Introduction
crispr_screen
is a free, open-source command-line tool that enables easy and
efficient differential expression analysis for CRISPR screens.
It is a recreation of the MAGeCK
algorithm, which is a form of the DESeq
method specifically applied for CRISPR screens. This tool extends the
MAGeCK
algorithm with the MAGeCK-INC
method, but also implements the αRRA
algorithm described in the original MAGeCK
paper.
It is a drop-in replacement of current differential expression analyses that is faster, more stable, and easier to use.